William H. Gittens

XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia

Nícolas C. Hoch, Hana Hanzlíková, Stuart L. Rulten et al. · Nature · 2016 · 271 citations · Full text

Life Sciences, Genetics, Molecular Genetics +10

Overlapping roles for PARP1 and PARP2 in the recruitment of endogenous XRCC1 and PNKP into oxidized chromatin

Hana Hanzlíková, William H. Gittens, Kateřina Krejčíková et al. · Nucleic Acids Research · 2016 · 206 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

XRCC1 prevents toxic PARP1 trapping during DNA base excision repair

Annie Albert Demin, Kouji Hirota, Masataka Tsuda et al. · Molecular Cell · 2021 · 201 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

A nucleotide resolution map of Top2-linked DNA breaks in the yeast and human genome

William H. Gittens, Dominic Johnson, Rachal M. Allison et al. · Nature Communications · 2019 · 107 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The Tomato Nucleotide-binding Leucine-rich Repeat Immune Receptor I-2 Couples DNA-binding to Nucleotide-binding Domain Nucleotide Exchange

Stepan Fenyk, Christopher H. Dixon, William H. Gittens et al. · Journal of Biological Chemistry · 2015 · 23 citations · Full text

Agriculture, Molecular Biology, Plant Biology +17