Specific and Efficient Regression of Cancers Harboring KRAS Mutation by Targeted RNA Replacement

Wild-Type <i>KRAS</i> Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer

Rafael G. Amado, Michael Wolf, Marc Peeters et al. · Journal of Clinical Oncology · 2008 · 3.2K citations · Full text

Medicine, Oncology, Pharmacotherapy +17

COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer

Simon Forbes, Nidhi Bindal, Sally Bamford et al. · Nucleic Acids Research · 2010 · 2.3K citations · Full text

Medicine, Genetics, Oncology +17

<i>KRAS</i> Mutations As an Independent Prognostic Factor in Patients With Advanced Colorectal Cancer Treated With Cetuximab

Astrid Lièvre, Jean‐Baptiste Bachet, Valérie Boige et al. · Journal of Clinical Oncology · 2008 · 1.5K citations · Full text

Medicine, Oncology, Pharmacology +17

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

Judith S. Sebolt–Leopold, David T. Dudley, Román Herrera et al. · Nature Medicine · 1999 · 969 citations

Medicine, Cancer Biology, Oncology +14

A small catalytic oligoribonucleotide

Olke C. Uhlenbeck · Nature · 1987 · 934 citations

Life Sciences, Biochemistry, Molecular Biology +9