A hybrid siRNA delivery complex for enhanced brain penetration and precise amyloid plaque targeting in Alzheimer’s disease mice

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor.

LA Greene, Arthur S. Tischler · Proceedings of the National Academy of Sciences · 1976 · 5.6K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly D. Oakley, Sarah L. Cole, Sreemathi Logan et al. · Journal of Neuroscience · 2006 · 3.6K citations · Full text

Life Sciences, Neurology, Neuroscience +17

Tricine–SDS-PAGE

Hermann Schägger · Nature Protocols · 2006 · 2.5K citations

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

Mark E. Davis, Jonathan E. Zuckerman, Chung Hang Jonathan Choi et al. · Nature · 2010 · 2.5K citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmacology +12

A nanoparticle-based strategy for the imaging of a broad range of tumours by nonlinear amplification of microenvironment signals

Yiguang Wang, Gang Huang, Christopher T. Hensley et al. · Nature Materials · 2013 · 770 citations · Full text

Medicine, Cancer Biology, Oncology +17