Concepedia

Fetal and adult progenitors give rise to unique populations of CD8+ T cells

Jocelyn Wang, Erin M. Wissink, Neva B. Watson, Norah L. Smith, Andrew Grimson, Brian D. Rudd

Blood · 2016 · 93 citations · 50 references

DOIFull text

Open access

Concepts

Abstract

Key Points Neonatal and adult CD8+ T cells adopt different fates after infection because they are derived from distinct progenitor cells. Lin28b may regulate the developmental switch from fetal to adult CD8+ T cells.

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