In vivo effect of borneol on rat hepatic CYP2B expression and activity

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism

Ping Wei, Jun Zhang, Margarete Egan-Hafley et al. · Nature · 2000 · 649 citations

Medicine, Molecular Biology, Pharmacology +13

Phenobarbital-Responsive Nuclear Translocation of the Receptor CAR in Induction of the<i>CYP2B</i>Gene

Takeshi Kawamoto, Tatsuya Sueyoshi, Igor N. Zelko et al. · Molecular and Cellular Biology · 1999 · 546 citations · Full text

Medicine, Molecular Biology, Pharmacology +12

Identification of a Novel Human Constitutive Androstane Receptor (CAR) Agonist and Its Use in the Identification of CAR Target Genes

Jodi M. Maglich, Derek J. Parks, Linda B. Moore et al. · Journal of Biological Chemistry · 2003 · 415 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Regulation of the Human CYP2B6 Gene by the Nuclear Pregnane X Receptor

Bryan Goodwin, Linda B. Moore, Catherine M. Stoltz et al. · Molecular Pharmacology · 2001 · 370 citations

Medicine, Molecular Biology, Pharmacology +16

The Orphan Nuclear Receptor Constitutive Active/Androstane Receptor Is Essential for Liver Tumor Promotion by Phenobarbital in Mice

Yukio Yamamoto, Rick Moore, Thomas L. Goldsworthy et al. · Cancer Research · 2004 · 346 citations

Medicine, Pharmacology, Toxicology +17