Concepedia

Intrahepatic cholangiocarcinoma frequently shows loss of <scp>BAP</scp>1 and <scp>PBRM</scp>1 expression, and demonstrates specific clinicopathological and genetic characteristics with <scp>BAP</scp>1 loss

Kento Misumi, Akimasa Hayashi, Junji Shibahara, Junichi Arita, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo, Masashi Fukayama

Histopathology · 2016 · 44 citations · 15 references

DOI

Abstract

BAP1 and PBRM1 loss is seen frequently in ICC. ICC with BAP1 loss shares features of small-duct type ICC.

References

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Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

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