Concepedia

Bap1 Loss

BAP1 Loss is a molecular biomarker characterized by the inactivation or absence of the BRCA1-associated protein 1 (BAP1) tumor suppressor, distinguished by its association with malignant pleural mesothelioma susceptibility and impaired DNA repair mechanisms.

295

Publications

24.7K

Citations

2.7K

Authors

724

Institutions

Publications per year

2017–2026

187

Parents

Publications

295

Frequent Mutation of <i>BAP1</i> in Metastasizing Uveal Melanomas

J. William Harbour, Michael D. Onken, Elisha Roberson et al. · Science · 2010 · 1.5K citations · Full text

, , +17

BAP1 links metabolic regulation of ferroptosis to tumour suppression

Yilei Zhang, Jiejun Shi, Xiaoguang Liu et al. · Nature Cell Biology · 2018 · 1K citations

, , +12

BAP1 loss defines a new class of renal cell carcinoma

Samuel Peña‐Llopis, Silvia Vega-Rubín-de-Celis, Arnold Liao et al. · Nature Genetics · 2012 · 995 citations · Full text

, , +13

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

Matthew J. Bott, Marie Brevet, Barry S. Taylor et al. · Nature Genetics · 2011 · 731 citations

, , +15

Germline mutations in BAP1 predispose to melanocytic tumors

Thomas Wiesner, Anna C. Obenauf, Rajmohan Murali et al. · Nature Genetics · 2011 · 724 citations

, , +14

1–5 of 295

Authors

2.7K

  1. AC
    Andrew Churg

    University of British Columbia, Canada

    12 publications · 1.1K citations

    12

    h-index

  2. JW
    J. William Harbour

    University of Miami, United States

    12 publications · 2.3K citations

    12

    h-index

  3. JB
    James Brugarolas

    The University of Texas Southwestern Medical Center, United States

    10 publications · 2.2K citations

    10

    h-index

  4. PK
    Payal Kapur

    The University of Texas Southwestern Medical Center, United States

    10 publications · 2.2K citations

    10

    h-index

  5. HI
    Harvey I. Pass

    New York University, United States

    10 publications · 2.3K citations

    9

    h-index

1–5 of 2.7K

Institutions

724

  1. Memorial Sloan Kettering Cancer Center

    New York, United States

    21 h-index

    169 publications

    56.1K citations

  2. The University of Texas Southwestern Medical Center

    Dallas, United States

    13 h-index

    82 publications

    27.4K citations

  3. Vancouver General Hospital

    Vancouver, Canada

    12 h-index

    21 publications

    2.1K citations

  4. The University of Texas MD Anderson Cancer Center

    Houston, United States

    11 h-index

    79 publications

    27.2K citations

  5. University of British Columbia

    Vancouver, Canada

    11 h-index

    30 publications

    2.8K citations

  6. Inserm

    Paris, France

    11 h-index

    79 publications

    2.8K citations

  7. Cornell University

    Ithaca, United States

    11 h-index

    49 publications

    9K citations

  8. University of Miami

    Coral Gables, United States

    10 h-index

    46 publications

    1.6K citations

1–8 of 724

Venues

  1. Cancers

    13 publications · 370 citations

    12

    h-index

  2. Modern Pathology

    9 publications · 795 citations

    9

    h-index

  3. The American Journal of Surgical Pathology

    9 publications · 1.1K citations

    9

    h-index

  4. Journal of Clinical Oncology

    8 publications · 307 citations

    8

    h-index

  5. Clinical Cancer Research

    7 publications · 906 citations

    7

    h-index

1–5