Concepedia

Direct interaction of human serum proteins with AAV virions to enhance AAV transduction: immediate impact on clinical applications

Mian Wang, Junjiang Sun, Ashley Crosby, Kenton Woodard, Matthew L. Hirsch, R. Jude Samulski, C Li

Gene Therapy · 2016 · 52 citations · 45 references

DOI

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References

45

Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

Catherine S. Manno, Glenn F. Pierce, Valder R. Arruda et al. · Nature Medicine · 2006 · 2.1K citations

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Adenovirus-Associated Virus Vector–Mediated Gene Transfer in Hemophilia B

Amit C. Nathwani, Edward G. D. Tuddenham, Savita Rangarajan et al. · New England Journal of Medicine · 2011 · 1.8K citations · Full text

, , +13

Production of High-Titer Recombinant Adeno-Associated Virus Vectors in the Absence of Helper Adenovirus

Xiao Xiao, Juan Li, R. Jude Samulski · Journal of Virology · 1998 · 1.4K citations · Full text

, , +10

Long-Term Safety and Efficacy of Factor IX Gene Therapy in Hemophilia B

Amit Nathwani, Ulreke M. Reiss, Edward G. D. Tuddenham et al. · New England Journal of Medicine · 2014 · 1.3K citations · Full text

, , +17

Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

F K Ferrari, T. V. Samulski, Thomas Shenk et al. · Journal of Virology · 1996 · 762 citations · Full text

, , +14