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IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Adam S. Darwich, Alison Margolskee, Xavier Pépin, Leon Aarons, Aleksandra Galetin, Amin Rostami‐Hodjegan, Sara Carlert, Maria Hammarberg, Constanze Hilgendorf, Pernilla Johansson,

European Journal of Pharmaceutical Sciences · 2016 · 45 citations · 13 references

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13

A Concordance Correlation Coefficient to Evaluate Reproducibility

Biometrics · 1989 · 8.7K citations

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Physiologically based pharmacokinetic modelling 2: Predicting the tissue distribution of acids, very weak bases, neutrals and zwitterions

Trudy Rodgers, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2006 · 940 citations

, , +11

Physiologically Based Pharmacokinetic Modeling 1: Predicting the Tissue Distribution of Moderate-to-Strong Bases

Trudy Rodgers, David E. Leahy, Malcolm Rowland · Journal of Pharmaceutical Sciences · 2005 · 774 citations

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A Priori Prediction of Tissue:Plasma Partition Coefficients of Drugs to Facilitate the Use of Physiologically‐Based Pharmacokinetic Models in Drug Discovery

Patrick Poulin, Frank‐Peter Theil · Journal of Pharmaceutical Sciences · 2000 · 423 citations

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Estimation of the Increase in Solubility of Drugs as a Function of Bile Salt Concentration

Sabena Dawoodali Mithani, Vassiliki Bakatselou, Christopher TenHoor et al. · Pharmaceutical Research · 1996 · 300 citations · Full text

, , +11