Concepedia

G-quadruplex DNA targeted metal complexes acting as potential anticancer drugs

Qian Cao, Yi Li, E. Freisinger, Peter Z. Qin, Roland K. O. Sigel, Zong‐Wan Mao

Inorganic Chemistry Frontiers · 2016 · 259 citations · 120 references

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Abstract

This review summarizes the recent development of G4 DNA targeted metal complexes and discusses their potential as anticancer drugs.

References

120

Direct evidence for a G-quadruplex in a promoter region and its targeting with a small molecule to repress c- <i>MYC</i> transcription

Adam Siddiqui-Jain, Cory L. Grand, David J. Bearss et al. · Proceedings of the National Academy of Sciences · 2002 · 2.2K citations

, , +17

Quantitative visualization of DNA G-quadruplex structures in human cells

Giulia Biffi, David Tannahill, John McCafferty et al. · Nature Chemistry · 2013 · 2.2K citations

, , +15

HELIX FORMATION BY GUANYLIC ACID

Martin Gellert, Marie N. Lipsett, David R. Davies · Proceedings of the National Academy of Sciences · 1962 · 1.6K citations · Full text

, , +8

A molecular light switch for DNA: Ru(bpy)2(dppz)2+

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The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity

Carol W. Greider, Elizabeth H. Blackburn · Cell · 1987 · 1.2K citations

, , +10