IRAKM‐Mincle axis links cell death to inflammation: Pathophysiological implications for chronic alcoholic liver disease

IRAK-M Is a Negative Regulator of Toll-like Receptor Signaling

Koichi S. Kobayashi, Lorraine D. Hernandez, Jorge E. Galán et al. · Cell · 2002 · 1.3K citations · Full text

Inflammation, Toll-like Receptors, Molecular Immunology +7

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

Su‐Chang Lin, Yu-Chih Lo, Hao Wu · Nature · 2010 · 1K citations · Full text

Signal Transduction, Signaling Pathway, Molecular Biology +4

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

Eri Ishikawa, Tetsuaki Ishikawa, Yasu S. Morita et al. · The Journal of Experimental Medicine · 2009 · 760 citations · Full text

Mincle is an ITAM-coupled activating receptor that senses damaged cells

Sho Yamasaki, Eri Ishikawa, Machie Sakuma et al. · Nature Immunology · 2008 · 726 citations

Molecular Physiology, Signal Transduction, Itam-coupled Activating Receptor +9

Increased intestinal permeability to macromolecules and endotoxemia in patients with chronic alcohol abuse in different stages of alcohol-induced liver disease

Alexandr Parlesak, Christian Schäfer, Tatjana Schütz et al. · Journal of Hepatology · 2000 · 634 citations

Intestinal Permeability, Chronic Alcohol Abuse, Hepatology +11