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Programmed Death-1 Ligand 2-Mediated Regulation of the PD-L1 to PD-1 Axis Is Essential for Establishing CD4 + T Cell Immunity

Deshapriya S. Karunarathne, Joshua M. Horne‐Debets, Johnny X. Huang, Rebecca J. Faleiro, Chiuan Yee Leow, Fiona H. Amante, Thomas S. Watkins, John J. Miles, Patrick Dwyer, Katryn J. Stacey,

Immunity · 2016 · 102 citations · 32 references

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32

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Gordon J. Freeman, Andrew J. Long, Yoshiko Iwai et al. · The Journal of Experimental Medicine · 2000 · 5.2K citations · Full text

, , +17

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman, Clive R. Wood, Tatyana Chernova et al. · Nature Immunology · 2001 · 2.9K citations

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

Cheryl L. Day, Daniel E. Kaufmann, Photini Kiepiela et al. · Nature · 2006 · 2.6K citations

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PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

Loise M. Francisco, Victor H. Salinas, Keturah Brown et al. · The Journal of Experimental Medicine · 2009 · 2K citations · Full text

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Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

Matthew M. Gubin, Xiuli Zhang, Heiko Schuster et al. · Nature · 2014 · 2K citations · Full text

, , +10