Concepedia

mTOR is a fine tuning molecule in CDK inhibitors-induced distinct cell death mechanisms via PI3K/AKT/mTOR signaling axis in prostate cancer cells

Özge Berrak, Elif Damla Arısan, Pınar Obakan Yerlikaya, Ajda Çoker Gürkan, Narçın Palavan-Ünsal

APOPTOSIS · 2016 · 21 citations · 45 references

DOI

Concepts

References

45

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

The EMBO Journal · 2000 · 6.5K citations · Full text

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Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

Dos D. Sarbassov, David A. Guertin, Siraj M. Ali et al. · Science · 2005 · 6.2K citations

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AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.8K citations · Full text

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Rictor, a Novel Binding Partner of mTOR, Defines a Rapamycin-Insensitive and Raptor-Independent Pathway that Regulates the Cytoskeleton

Dos D. Sarbassov, Siraj M. Ali, Do‐Hyung Kim et al. · Current Biology · 2004 · 2.7K citations · Full text

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Glycogen synthase kinase-3β regulates cyclin D1 proteolysis and subcellular localization

J. Alan Diehl, Mangeng Cheng, Martine F. Roussel et al. · Genes & Development · 1998 · 2.1K citations · Full text

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