The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability

A Small Ubiquitin-Related Polypeptide Involved in Targeting RanGAP1 to Nuclear Pore Complex Protein RanBP2

Rohit Mahajan, Christian Delphin, Tinglu Guan et al. · Cell · 1997 · 1.2K citations · Full text

Protein Function, Signal Transduction, Medicine +9

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

Michael H. Tatham, Marie‐Claude Geoffroy, Linnan Shen et al. · Nature Cell Biology · 2008 · 821 citations · Full text

Protein Function, Natural Sciences, Metalloprotein +8

The Nucleoporin RanBP2 Has SUMO1 E3 Ligase Activity

Andrea Pichler, Andreas Gast, Jacob-S. Seeler et al. · Cell · 2002 · 799 citations · Full text

Biochemistry, Natural Sciences, Molecular Biology +2

Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML

Xiaowei Zhang, Xiaojing Yan, Zi‐Ren Zhou et al. · Science · 2010 · 765 citations

Apoptosis, Arsenic Trioxide Controls, Molecular Biology +18

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

Valérie Lallemand-Breitenbach, Marion Jeanne, Shirine Benhenda et al. · Nature Cell Biology · 2008 · 705 citations

Reductive Stress, Redox Signaling, Cell Signaling +9