Valérie Lallemand-Breitenbach

Arsenic Trioxide Controls the Fate of the PML-RARα Oncoprotein by Directly Binding PML

Xiaowei Zhang, Zi‐Ren Zhou, Feifei Yang et al. · Science · 2010 · 775 citations

Medicine, Molecular Biology, Oncology +13

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

Valérie Lallemand-Breitenbach, Marion Jeanne, Shirine Benhenda et al. · Nature Cell Biology · 2008 · 715 citations

Life Sciences, Cell Biology, Molecular Biology +9

Role of Promyelocytic Leukemia (Pml) Sumolation in Nuclear Body Formation, 11s Proteasome Recruitment, and as2O3-Induced Pml or Pml/Retinoic Acid Receptor α Degradation

Valérie Lallemand-Breitenbach, Jun Zhu, F Puvion et al. · The Journal of Experimental Medicine · 2001 · 482 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation

Rihab Nasr, Marie-Claude Guillemin, Omar Ferhi et al. · Nature Medicine · 2008 · 350 citations

Medicine, Cell Biology, Oncology +9

PML/RARA Oxidation and Arsenic Binding Initiate the Antileukemia Response of As2O3

Marion Jeanne, Valérie Lallemand-Breitenbach, Omar Ferhi et al. · Cancer Cell · 2010 · 338 citations · Full text

Life Sciences, Chemistry, Hematology +11