The effect of Liuwei Dihuang decoction on PI3K/Akt signaling pathway in liver of type 2 diabetes mellitus (T2DM) rats with insulin resistance

IDF Diabetes Atlas: Global estimates of the prevalence of diabetes for 2011 and 2030

David Whiting, Leonor Guariguata, Clara Weil et al. · Diabetes Research and Clinical Practice · 2011 · 4K citations

Medicine, Chronic Disease Prevention, Endocrinology +12

Disruption of IRS-2 causes type 2 diabetes in mice

Dominic J. Withers, Julio Sanchez Gutierrez, Heather Towery et al. · Nature · 1998 · 1.8K citations

Life Sciences, Endocrinology, Molecular Biology +12

Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse.

Nada Kerouz, Dieter Hörsch, Sebastián Pons et al. · Journal of Clinical Investigation · 1997 · 305 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Mild Electrical Stimulation with Heat Shock Ameliorates Insulin Resistance via Enhanced Insulin Signaling

Saori Morino, Tatsuya Kondo, Kazunari Sasaki et al. · PLoS ONE · 2008 · 79 citations · Full text

Life Sciences, Molecular Biology, Physiology +16

Antihyperglycemic effect of the traditional Chinese scutellaria–coptis herb couple and its main components in streptozotocin-induced diabetic rats

Sheng-Zi Liu, Yuan‐Xiong Deng, Bo Chen et al. · Journal of Ethnopharmacology · 2012 · 43 citations

Medicine, Botany, Pharmacology +11