Concepedia

RVX-297- a novel BD2 selective inhibitor of BET bromodomains

Olesya A. Kharenko, Emily M. Gesner, Reena G. Patel, Karen Norek, André White, Eric Fontano, R.K. Suto, Peter R. Young, Kevin G. McLure, Henrik C. Hansen

Biochemical and Biophysical Research Communications · 2016 · 55 citations · 9 references

DOI

Concepts

References

9

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

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Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud et al. · Nature · 2010 · 4.3K citations · Full text

, , +5

Suppression of inflammation by a synthetic histone mimic

Edwige Nicodème, Kate L. Jeffrey, Uwe Schaefer et al. · Nature · 2010 · 1.6K citations · Full text

, , +12

RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain

S. Picaud, Christopher Wells, I. Felletar et al. · Proceedings of the National Academy of Sciences · 2013 · 481 citations · Full text

, , +11

RVX-208

Dana Bailey, Ravi Jahagirdar, Allan Gordon et al. · Journal of the American College of Cardiology · 2010 · 229 citations