Concepedia

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool

Ragna Sannerud, Cary Esselens, Paulina Ejsmont, Rafael Mattera, Leïla Rochin, Arun Kumar Tharkeshwar, Greet De Baets, Veerle De Wever, R. Habets, Veerle Baert,

Cell · 2016 · 290 citations · 32 references

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32

The FoldX web server: an online force field

Joost Schymkowitz, Jean‐Paul Borg, François Stricher et al. · Nucleic Acids Research · 2005 · 2.9K citations · Full text

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Increasing the precision of comparative models with YASARA NOVA—a self‐parameterizing force field

Elmar Krieger, Günther Koraimann, Gert Vriend · Proteins Structure Function and Bioinformatics · 2002 · 1.5K citations · Full text

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Reconstitution of γ-secretase activity

Dieter Edbauer, Edith Winkler, Jörg T. Regula et al. · Nature Cell Biology · 2003 · 875 citations

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The role of presenilin cofactors in the γ-secretase complex

Nobumasa Takasugi, Taisuke Tomita, Ikuo Hayashi et al. · Nature · 2003 · 867 citations

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Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome

Anne M. Cataldo, Corrinne M. Peterhoff, Juan C. Troncoso et al. · American Journal Of Pathology · 2000 · 850 citations · Full text

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