Arun Kumar Tharkeshwar

Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool

Ragna Sannerud, Cary Esselens, Paulina Ejsmont et al. · Cell · 2016 · 284 citations · Full text

Intracellular Aβ Pool, Protein Secretion, Protein Function +10

A novel approach to analyze lysosomal dysfunctions through subcellular proteomics and lipidomics: the case of NPC1 deficiency

Arun Kumar Tharkeshwar, Jesse Trekker, Wendy Vermeire et al. · Scientific Reports · 2017 · 121 citations · Full text

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

William Hancock‐Cerutti, Zheng Wu, Peng Xu et al. · The Journal of Cell Biology · 2022 · 100 citations · Full text

PQLC2 recruits the C9orf72 complex to lysosomes in response to cationic amino acid starvation

Joseph Amick, Arun Kumar Tharkeshwar, Gabriel Talaia et al. · The Journal of Cell Biology · 2019 · 59 citations · Full text

A novel strategy for the comprehensive analysis of the biomolecular composition of isolated plasma membranes

Deepak B. Thimiri Govinda Raj, Bart Ghesquière, Arun Kumar Tharkeshwar et al. · Molecular Systems Biology · 2011 · 43 citations · Full text