Complex environment experience rescues impaired neurogenesis, enhances synaptic plasticity, and attenuates neuropathology in familial Alzheimer's disease‐linked APPswe/PS1ΔE9 mice

Yuan‐Shih Hu, Peng Xu, Gustavo Pigino, +3

The FASEB Journal

BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression

Peng Xu, Elizabeth A. Raetz, Mayumi Kitagawa, +2

Biology Open

ChromatinChromosome StabilityCell RegulationCell DivisionGenetics +10

ER-lysosome lipid transfer protein VPS13C/PARK23 prevents aberrant mtDNA-dependent STING signaling

William Hancock‐Cerutti, Zheng Wu, Peng Xu, +6

The Journal of Cell Biology

MAPK8 mediates resistance to temozolomide and apoptosis of glioblastoma cells through MAPK signaling pathway

Peng Xu, Guofeng Zhang, Shuangxing Hou, +1

Biomedicine & Pharmacotherapy

Signal TransductionSignaling PathwayReceptor Tyrosine KinaseApoptosisAutophagy +9

GSAP modulates γ-secretase specificity by inducing conformational change in PS1

Eitan Wong, George P. Liao, Jerry C. Chang, +3

Proceedings of the National Academy of Sciences

Pyrvinium selectively targets blast phase-chronic myeloid leukemia through inhibition of mitochondrial respiration

Wei Xiang, Jit Kong Cheong, Shi Hui Ang, +8

Oncotarget

The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage

Peng Xu, Amanda Bentley‐DeSousa, William Hancock‐Cerutti, +8

Nature Cell Biology

Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via Smad-Dependent and Smad-Independent Signaling Pathways

Xianlong Zhou, Peng Xu, Haihua Chen, +7

Scientific Reports

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyPulmonary Alveolar Proteinosis +23

GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer’s disease

Peng Xu, Jerry C. Chang, Xiaopu Zhou, +13

The Journal of Experimental Medicine

AgingGeneticsAlzheimer ’Synaptic SignalingAlzheimer's Disease +18

B56-PP2A regulates motor dynamics for mitotic chromosome alignment

Peng Xu, David M. Virshup, Sang Hyun Lee

Journal of Cell Science

ChromatinCell DivisionProper AlignmentGeneticsAutophagy +13