Eitan Wong

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Ji‐Yeun Hur, Georgia Frost, Xianzhong Wu et al. · Nature · 2020 · 360 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +8

ADAM17 substrate release in proximal tubule drives kidney fibrosis

Eirini Kefaloyianni, Muthu Lakshmi Muthu, Jakob Kaeppler et al. · JCI Insight · 2016 · 126 citations · Full text

Renal Pathology, Immunology, Renal Inflammation +24

The Functional Maturation of A Disintegrin and Metalloproteinase (ADAM) 9, 10, and 17 Requires Processing at a Newly Identified Proprotein Convertase (PC) Cleavage Site

Eitan Wong, Thorsten Maretzky, Yoav Peleg et al. · Journal of Biological Chemistry · 2015 · 83 citations · Full text

Protein Expression, Cleavage Site, Protein Folding +8

Harnessing the natural inhibitory domain to control TNFα Converting Enzyme (TACE) activity in vivo

Eitan Wong, Tal Cohen, Erez Romi et al. · Scientific Reports · 2016 · 82 citations · Full text

GSAP modulates γ-secretase specificity by inducing conformational change in PS1

Eitan Wong, George P. Liao, Jerry C. Chang et al. · Proceedings of the National Academy of Sciences · 2019 · 57 citations · Full text