Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Elizabeth H. Corder, Ann M. Saunders, Warren J. Strittmatter et al. · Science · 1993 · 9.5K citations

Life Sciences, Genetics, Neurology +17

The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

Suzanne S. Mirra, Albert Heyman, Daniel W. McKeel et al. · Neurology · 1991 · 5.1K citations

Medicine, Genetics, Neurology +17

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David Borchelt, Gopal Thinakaran, Christopher B. Eckman et al. · Neuron · 1996 · 1.5K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

Cecilia Bucci, Robert G. Parton, Ian H. Mather et al. · Cell · 1992 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11