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<i>ABCB1</i> 1199G&gt;A Polymorphism (rs2229109) Affects the Transport of Imatinib, Nilotinib and Dasatinib

DOI

29

Citations

15

References

2016

Year

Géraldine Dessilly, Laure Elens, Nadtha Panin, Linda Karmani, Jean‐Baptiste Demoulin, Vincent Haufroid
Pharmacogenomics

Abstract

Imatinib, nilotinib and dasatinib are transported more efficiently by the ABCB1 variant (Asn400) compared with the wild-type (Ser400) protein. The impact of ABCB1 1199G>A SNP on TKI response should be further investigated in chronic myelogenous leukemia patients.

References

YearCitations

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