Concepedia

<i>UGT1A6</i> - and <i>UGT2B7</i> -Related Valproic Acid Pharmacogenomics According to Age Groups and Total Drug Concentration Levels

Dimitrios Chatzistefanidis, Leandros Lazaros, Katerina Giaka, Iliada Nakou, Meropi Tzoufi, Ioannis Georgiou, Athanassios P. Kyritsis, Sofia Markoula

Pharmacogenomics · 2016 · 16 citations · 45 references

DOI

Abstract

UGT1A6 and UGT2B7 genotypes were not related to significant changes in VPA metabolism, even after controlling for total drug concentration levels. Younger ages were associated with increased VPA clearance rate.

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