Concepedia

Specific Knockdown of Endogenous Tau Protein by Peptide-Directed Ubiquitin-Proteasome Degradation

Tingting Chu, Na Gao, Qianqian Li, Pu‐Guang Chen, Xifei Yang, Yong‐Xiang Chen, Yufen Zhao, Yanmei Li

Cell chemical biology · 2016 · 241 citations · 41 references

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41

Protacs: Chimeric molecules that target proteins to the Skp1–Cullin–F box complex for ubiquitination and degradation

Kathleen M. Sakamoto, Kyung B. Kim, Akiko Kumagai et al. · Proceedings of the National Academy of Sciences · 2001 · 2.5K citations · Full text

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Receptor Interacting Protein Kinase-3 Determines Cellular Necrotic Response to TNF-α

Sudan He, Lai Wang, Lin Miao et al. · Cell · 2009 · 2.2K citations

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Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model

Erik D. Roberson, Kimberly Scearce‐Levie, Jorge J. Palop et al. · Science · 2007 · 1.9K citations

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An auxin-based degron system for the rapid depletion of proteins in nonplant cells

Kohei Nishimura, Tatsuo Fukagawa, Haruhiko Takisawa et al. · Nature Methods · 2009 · 1.8K citations

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Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

Lars M. Ittner, Yazi D. Ke, Fabien Delerue et al. · Cell · 2010 · 1.8K citations · Full text

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