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Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling

Molecular PharmacologyDrug TargetMedicineNatural SciencesRational Drug DesignMolecular BiologyCompound ProfilingDrug DevelopmentPharmacologyMolecular ModelingSmall MoleculesDrug DiscoveryQuantitative Pharmacology