Nobuko Nishimura

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 722 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Species-Specific Pharmacology of Trichloro(Sulfanyl)ethyl Benzamides as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists

Lana Klionsky, Rami Tamir, BaoXi Gao et al. · Molecular Pain · 2007 · 109 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Novel Vanilloid Receptor-1 Antagonists:  3. The Identification of a Second-Generation Clinical Candidate with Improved Physicochemical and Pharmacokinetic Properties

Huiling Wang, Jodie G. Katon, Balan Chenera et al. · Journal of Medicinal Chemistry · 2007 · 72 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Phospshoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Discovery and Structure–Activity Relationships of a Series of Quinoline and Quinoxaline Derivatives

Nobuko Nishimura, Aaron Siegmund, Longbin Liu et al. · Journal of Medicinal Chemistry · 2011 · 60 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Fused Piperidines as a Novel Class of Potent and Orally Available Transient Receptor Potential Melastatin Type 8 (TRPM8) Antagonists

Nuria Tamayo, Yunxin Bo, Vijay Gore et al. · Journal of Medicinal Chemistry · 2012 · 55 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15