Concepedia

Growth factor-dependent activation of the Ras-Raf-MEK-MAPK pathway in the human pancreatic carcinoma cell line PANC-1 carrying activated K-ras: implications for cell proliferation and cell migration

Klaudia Giehl, Bettina Skripczynski, Angela Mansard, André Menke, Peter Gierschik

Oncogene · 2000 · 114 citations · 42 references

DOI

Concepts

References

42

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

Hermann Schägger, Gebhard von Jagow · Analytical Biochemistry · 1987 · 11.5K citations

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The MAPK signaling cascade

Rony Seger, Edwin G. Krebs · The FASEB Journal · 1995 · 3.4K citations

, , +17

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

David T. Dudley, Long Pang, Stuart J. Decker et al. · Proceedings of the National Academy of Sciences · 1995 · 2.7K citations · Full text

, , +15

Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

László Buday, Julian Downward · Cell · 1993 · 1.1K citations

, , +11

Role of Phosphoinositide 3-OH Kinase in Cell Transformation and Control of the Actin Cytoskeleton by Ras

Pablo Rodriguez‐Viciana, Patricia H. Warne, Asim Khwaja et al. · Cell · 1997 · 1.1K citations · Full text

, , +16