Oncogene · 1999 · 121 citations · 27 references
Life SciencesCell BiologyMolecular BiologyApoptosisEnzymologySignal TransductionApoptosis RegulationApoptotic Signal TransductionApoptotic SignalingCaspase ActivationDna Damage SignalingDna Damage-induced ApoptosisApoptosis-related Dna DamageCaspase CleavageCaspase SignalingCaspase-mediated ApoptosisCaspase-mediated ProteolysisDna CleavageDna Cleavage Mechanism
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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
Masato Enari, Hideki Sakahira, Hideki Yokoyama et al. · Nature · 1998 · 3.2K citations
The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis
Naoto Itoh, Shin Yonehara, Ai Ishii et al. · Cell · 1991 · 2.8K citations
Thymocyte apoptosis induced by p53-dependent and independent pathways
Alan R. Clarke, Colin A. Purdie, David J. Harrison et al. · Nature · 1993 · 2.3K citations