Regression of intracerebral rat glioma isografts by therapeutic subcutaneous immunization with interferon-γ, interleukin-7, or B7-1-transfected tumor cells

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

Glen Dranoff, Elizabeth M. Jaffee, A Lazenby et al. · Proceedings of the National Academy of Sciences · 1993 · 2.8K citations

Medicine, Immunology, Oncology +17

CTLA-4 is a second receptor for the B cell activation antigen B7.

Peter S. Linsley, William Brady, M Urnes et al. · The Journal of Experimental Medicine · 1991 · 1.7K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

A safe packaging line for gene transfer: separating viral genes on two different plasmids

Dina Markowitz, Stephen P. Goff, A Bank · Journal of Virology · 1988 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

Lieping Chen, Stephanie Ashe, William Brady et al. · Cell · 1992 · 1.1K citations

Life Sciences, Immunology, Oncology +16

Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

Robert L. Martuza, Amy Malick, James M. Markert et al. · Science · 1991 · 1K citations

Medicine, Cancer Biology, Oncology +14