The Effect of Tertiary Butyl Alcohol on the Resistance of the Dry Product Layer During Primary Drying

The collapse temperature in freeze drying: Dependence on measurement methodology and rate of water removal from the glassy phase

Michael J. Pikal, Saroj Shah · International Journal of Pharmaceutics · 1990 · 305 citations

Pharmacy, Food Science, Food Preservation +13

Physical Chemistry of Freeze-drying: Measurement of Sublimation Rates for Frozen Aqueous Solutions by a Microbalance Technique

Michael J. Pikal, Saroj Shah, David E. Senior et al. · Journal of Pharmaceutical Sciences · 1983 · 195 citations

Pharmacy, Biochemistry, Chemistry +10

Thermal Analysis of the Tertiary Butyl Alcohol-Water System and Its Implications on Freeze-Drying

Kasra Kasraian, Patrick P. DeLuca · Pharmaceutical Research · 1995 · 118 citations

Pharmacy, Biochemistry, Food Science +13

The effects of additives on the stability of freeze-dried β-galactosidase stored at elevated temperature

Ken‐ichi Izutsu, Sumie Yoshioka, Yasushi Takeda · International Journal of Pharmaceutics · 1991 · 82 citations

Agriculture, Biochemistry, Food Science +11

Use of lyoprotectants in the freeze-drying of a model protein, ribonuclease A.

Michael Townsend, Patrick P. DeLuca · PubMed · 1989 · 63 citations

Life Sciences, Biochemistry, Molecular Biology +17