Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach

Multicomponent Reactions with Isocyanides

Alexander Dömlingꝉ, Ivar Ugi · Angewandte Chemie International Edition · 2000 · 4K citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Studies on the Metabolism of Troglitazone to Reactive Intermediates in Vitro and in Vivo. Evidence for Novel Biotransformation Pathways Involving Quinone Methide Formation and Thiazolidinedione Ring Scission

Kelem Kassahun, Paul G. Pearson, Wei Tang et al. · Chemical Research in Toxicology · 2000 · 307 citations

Medicine, Pharmacology, Toxicology +14

High Throughput Screening of Physicochemical Properties and In Vitro ADME Profiling in Drug Discovery

Hong Wan, Anders Holmén · Combinatorial Chemistry & High Throughput Screening · 2009 · 97 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Characterization of Potassium Channel Modulators with QPatch ^™ Automated Patch-Clamp Technology: System Characteristics and Performance

Jonatan Kutchinsky, Søren Friis, Margit Asmild et al. · Assay and Drug Development Technologies · 2003 · 84 citations

Natural Sciences, Bioengineering, Biophysics +17

Studies on the sequential multi-component coupling/Diels–Alder cycloaddition reaction

Dennis L. Wright, Claude V. Robotham, Khalil Aboud · Tetrahedron Letters · 2002 · 76 citations

Natural Sciences, Chemistry, Organic Chemistry +8