Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis

ras oncogenes in human cancer: a review.

Joyce Bos · PubMed · 1989 · 5.1K citations

Ras Gene Mutations, Tumor Biology, Ras Oncogenes +15

A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma

Marta Puyol, Alberto Martín, Pierre Dubus et al. · Cancer Cell · 2010 · 408 citations · Full text

Oncogenic Agent, Medicine, Synthetic Lethal Interaction +11

Wildtype Kras2 can inhibit lung carcinogenesis in mice

Zhongqiu Zhang, Yian Wang, Haris G. Vikis et al. · Nature Genetics · 2001 · 297 citations

Tumor Biology, Lung Inflammation, Oncogenic Agent +6

Genetic changes in skin tumor progression: Correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7

Rod Bremner, Allan Balmain · Cell · 1990 · 267 citations

Tumor Biology, Skin Tumor Progression, Mutant Ras Gene +9

Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

Iris T. Chan, Jeffery L. Kutok, Ifor R. Williams et al. · Journal of Clinical Investigation · 2004 · 260 citations · Full text