Activation of oligodendroglial Stat3 is required for efficient remyelination

Andrew J. Steelman, Yun Zhou, Hisami Koito, +4

Neurobiology of Disease

Molecular NeuroscienceMedicineOligodendroglial Stat3Brain-immune InteractionNeurology +6

Single-nucleotide human disease mutation inactivates a blood-regenerative GATA2 enhancer

Alexandra A. Soukup, Ye Zheng, Charu Mehta, +10

Journal of Clinical Investigation

Blood-regenerative Gata2 EnhancerGene TherapiesGata-binding Protein 2Developmental BiologyCell Regulation +11

Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia–reperfusion through Adenosine 5′-monophosphate-activated protein kinase–sirtuin1 pathway

Huirong Jing, Jihong Yao, Xingming Liu, +5

Journal of Surgical Research

Acute Lung InjuryInflammationAnti-inflammatoryLung InflammationFatty Acids +7

Loss of Dnmt3a and endogenous KrasG12D/+ cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis

Yi Chang, Xiaona You, Guangyao Kong, +7

Leukemia

Lineage PlasticityDevelopmental BiologyCell RegulationMedicineStem Cell Research +10

<i>Asxl1</i> loss cooperates with oncogenic <i>Nras</i> in mice to reprogram the immune microenvironment and drive leukemic transformation

Xiaona You, Fabao Liu, Moritz Binder, +26

Blood

Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis

Guangyao Kong, Yi Chang, Alisa Damnernsawad, +10

Leukemia

Developmental BiologyOncogenic Kras-induced LeukemogenesisOncogenic AgentWild-type KrasRas Isoforms +8

Expression of <i>Nras</i> <i>Q61R</i> and <i>MYC</i> transgene in germinal center B cells induces a highly malignant multiple myeloma in mice

Zhi Wen, Adhithi Rajagopalan, Evan Flietner, +22

Blood

p53 −/− synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia

Jingfang Zhang, Guangyao Kong, Adhithi Rajagopalan, +17

Blood

Unique dependence on Sos1 in KrasG12D-induced leukemogenesis

Xiaona You, Guangyao Kong, Erik A. Ranheim, +3

Blood

<i>Kras</i> is Required for Adult Hematopoiesis

Alisa Damnernsawad, Guangyao Kong, Zhi Wen, +9

Stem Cells

InflammationAdult Bone MarrowDevelopmental BiologyStem CellsHematology +13