Systematic diversification of benzylidene heterocycles yields novel inhibitor scaffolds selective for Dyrk1A, Clk1 and CK2

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Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis

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Defining Desirable Central Nervous System Drug Space through the Alignment of Molecular Properties, in Vitro ADME, and Safety Attributes

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The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bɛ at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase

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Life Sciences, Cell Biology, Molecular Biology +16

Gene expression profiling identifies molecular subtypes of gliomas

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