Concepedia
Statistics
Publications
37
Citations
4.5K
H-Index
33
Active since
1999
Affiliations
Merck Serono S.A. (Switzerland)(Current)
University of Turin
Medicines for Malaria Venture
University of Basel
Q-Pharm
Thomas Rückle is an author at Merck Serono S.A. (Switzerland) specializing in life sciences, pi3k signaling, and pharmacology.
Publications per year
1999–2021
Blockade of PI3Kγ suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
Montserrat Camps, Thomas Rückle, Hong Ji et al. · Nature Medicine · 2005 · 751 citations
Life Sciences, Immunology, Pharmacology +15
PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus
Domingo F. Barber, Almira Bartolomé, Carmen Hernández et al. · Nature Medicine · 2005 · 313 citations
Medicine, Immunology, Nephrology +15
The p110δ structure: mechanisms for selectivity and potency of new PI(3)K inhibitors
Alex Berndt, Simon Miller, Olusegun Williams et al. · Nature Chemical Biology · 2010 · 292 citations · Full text
Pharmacy, Medicinal Chemistry, Pharmacology +15
Phosphoinositide 3-Kinase p110β Activity: Key Role in Metabolism and Mammary Gland Cancer but Not Development
Elisa Ciraolo, Manuela Iezzi, Romina Marone et al. · Science Signaling · 2008 · 265 citations · Full text
Life Sciences, Biochemistry, Molecular Biology +17
Key role of the p110δ isoform of PI3K in B-cell antigen and IL-4 receptor signaling: comparative analysis of genetic and pharmacologic interference with p110δ function in B cells
Antonio Bilancio, Klaus Okkenhaug, Montserrat Camps et al. · Blood · 2005 · 211 citations
Life Sciences, Cell Biology, Immunology +16
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