Xenotransplantation makes a comeback

Production of α-1,3-Galactosyltransferase Knockout Pigs by Nuclear Transfer Cloning

Liangxue Lai, Donna Kolber‐Simonds, Kwang‐Wook Park et al. · Science · 2002 · 1.3K citations

Veterinary Medicine, Biotechnology, Genetics +17

Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs

Yifan Dai, Todd Vaught, Jeremy Boone et al. · Nature Biotechnology · 2002 · 710 citations

Agriculture, Genetics, Molecular Genetics +9

Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

Luhan Yang, Marc Güell, Dong Niu et al. · Science · 2015 · 619 citations · Full text

Life Sciences, Biotechnology, Genetics +16

Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue

Kazuhiko Yamada, Koji Yazawa, Akira Shimizu et al. · Nature Medicine · 2004 · 607 citations

Medicine, Nephrology, Surgery +12

Production of α-1,3-galactosyltransferase null pigs by means of nuclear transfer with fibroblasts bearing loss of heterozygosity mutations

Donna Kolber‐Simonds, Liangxue Lai, Steven R. Watt et al. · Proceedings of the National Academy of Sciences · 2004 · 458 citations · Full text

Life Sciences, Genetics, Molecular Genetics +13