Cloned pigs produced by nuclear transfer from adult somatic cells

Irina A. Polejaeva, Shu-Hung Chen, Todd Vaught, +9

Nature

BiologySomatic Cell GeneticsGenetic EngineeringCell CultureNuclear Transfer +6

Production of α1,3-Galactosyltransferase-Deficient Pigs

Carol J. Phelps, Chihiro Koike, Todd Vaught, +20

Science

Construction of adenovirus vectors through Cre-lox recombination

S. Hardy, Marina Kitamura, T Harris-Stansil, +2

Journal of Virology

Single Loxp SiteEngineeringSynthetic VirologyNatural SciencesLoxp Sites +12

Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs

Yifan Dai, Todd Vaught, Jeremy Boone, +12

Nature Biotechnology

Protein ExpressionGeneticsGenetic EngineeringMolecular GeneticsCloned Pigs +4

Generation of cloned transgenic pigs rich in omega-3 fatty acids

Liangxue Lai, Jing X. Kang, Rongfeng Li, +13

Nature Biotechnology

Developmental BiologyEngineeringOmega-3 Fatty AcidAnimal NutritionGenetics +9

Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys

Gang Chen, Hua Qian, Thomas E. Starzl, +17

Nature Medicine

HistocompatibilityTransplant RejectionUrologyXenotransplantationAutoimmune Disease +11

Gene therapy via primary myoblasts: long-term expression of factor IX protein following transplantation in vivo.

Yifan Dai, Mark Roman, Robert K. Naviaux, +1

Proceedings of the National Academy of Sciences

Cell TherapyIn Vivo Gene TherapyImmunologyViral PathogenesisPathology +20

Omega-3 polyunsaturated fatty acids inhibit hepatocellular carcinoma cell growth through blocking β-catenin and cyclooxygenase-2

Kyu Lim, Chang Han, Yifan Dai, +2

Molecular Cancer Therapeutics

Autologous bone marrow-derived rat mesenchymal stem cells promote PDX-1 and insulin expression in the islets, alter T cell cytokine pattern and preserve regulatory T cells in the periphery and induce sustained normoglycemia

Imene Boumaza, Suganya Srinivasan, William T. Witt, +4

Journal of Autoimmunity

Regenerative MedicineCell TherapyAutoimmune DiseaseMedicineStem Cell Transplantation +10

Sustained high-level expression of full-length human factor VIII and restoration of clotting activity in hemophilic mice using a minimal adenovirus vector

Cristina Balagué, Jiemin Zhou, Yifan Dai, +10

Blood