Alkaloids derived from flowers of Senna spectabilis, (−)-cassine and (−)-spectaline, have antiproliferative activity on HepG2 cells for inducing cell cycle arrest in G1/S transition through ERK inactivation and downregulation of cyclin D1 expression

Publication | Open Access

DOI Full Paper Access

Citations

References

2015

Year

Rodrigo Machado Pereira, Guilherme Álvaro Ferreira‐Silva, Marcos Pivatto, Luciana de Ávila Santos, Vanderlan da Silva Bolzani, Daniela Aparecida Chagas‐Paula, Jaqueline Carvalho de Oliveira, Cláudio Viegas, Marisa Ionta

Toxicology in Vitro

Signal TransductionChemoprevention StrategyBiochemistryErk InactivationMedicineSenna SpectabilisCellular PharmacologyCell Cycle ArrestPhytopharmacologyCell CycleAnti-cancer AgentPharmacologyCell BiologyCell Signaling