Concepedia

Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles

Jie Zhang, Utkarsh Doshi, Ayako Suzuki, Ching‐Wei Chang, Jürgen Borlak, Albert P. Li, Weida Tong

Chemico-Biological Interactions · 2015 · 44 citations · 21 references

DOI

Concepts

References

21

Comparing the Areas under Two or More Correlated Receiver Operating Characteristic Curves: A Nonparametric Approach

Elizabeth R. DeLong, David M. DeLong, Daniel L. Clarke‐Pearson · Biometrics · 1988 · 22.3K citations

, , +16

HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin

Ann K. Daly, Peter T. Donaldson, Pallav Bhatnagar et al. · Nature Genetics · 2009 · 1K citations

, , +14

Hepatotoxicity. The adverse effects of drugs and other chemicals on the liver

Food and Cosmetics Toxicology · 1980 · 695 citations

, , +14

Hepatotoxicity: The adverse effects of drugs and other chemicals on the liver

Willis C. Maddrey · Gastroenterology · 2000 · 648 citations · Full text

, , +14

Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

Jinghai J. Xu, Peter Henstock, Margaret C. Dunn et al. · Toxicological Sciences · 2008 · 492 citations · Full text

, , +17