Utkarsh Doshi

Human Enterocytes as an In Vitro Model for the Evaluation of Intestinal Drug Metabolism: Characterization of Drug-Metabolizing Enzyme Activities of Cryopreserved Human Enterocytes from Twenty-Four Donors

Ming-Chih David Ho, N J Ring, Kirsten Amaral et al. · Drug Metabolism and Disposition · 2017 · 50 citations

Medicine, Biochemistry, Pharmacology +11

Evaluation of multiple mechanism-based toxicity endpoints in primary cultured human hepatocytes for the identification of drugs with clinical hepatotoxicity: Results from 152 marketed drugs with known liver injury profiles

Jie Zhang, Utkarsh Doshi, Ayako Suzuki et al. · Chemico-Biological Interactions · 2015 · 44 citations

Pharmacy, Pharmacology, Toxicology +17

In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries

Utkarsh Doshi, Carol Loretz, Albert P. Li · Chemico-Biological Interactions · 2015 · 33 citations

Pharmacy, Pharmacology, Toxicology +15

Luciferin IPA–Based Higher Throughput Human Hepatocyte Screening Assays for CYP3A4 Inhibition and Induction

Utkarsh Doshi, Albert P. Li · SLAS DISCOVERY · 2011 · 32 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Endoplasmic Reticulum Stress Induction and ERK1/2 Activation Contribute to Nefazodone-Induced Toxicity in Hepatic Cells

Zhen Ren, Si Chen, Jie Zhang et al. · Toxicological Sciences · 2016 · 29 citations · Full text

Pharmacy, Pharmacology, Toxicology +17