Publication | Open Access

Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression

InflammationAnti-inflammatoryBiochemistryLipid PeroxidationImmunologyChronic InflammationMetabolic RegulationPyruvate DehydrogenaseEnable Cytokine ExpressionMetabolismMedicineCell BiologyRedox BiologyOxidative Stress