Publication | Open Access

Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF.

InflammationCytokineSignal TransductionAutoimmune DiseaseG Protein-coupled ReceptorIl-5 ReceptorsImmune RegulationImmunologyImmunologic MechanismAutoimmunityHuman Gm-csfCommon Beta ChainImmune SystemMedicineCell Biology