Timothy R. Hercus - Concepedia

Author

Timothy R. Hercus

Also Known As

T R Hercus, T. Hercus, T. R. Hercus, T.R. Hercus, Timothy Hercus, Timothy R Hercus, Timothy R. Hercus, Timothy R. Hercus

129

Publications

2.4K

Citations

H-Index

Concepts

All Affiliations

South Australia Pathology Centre for Cancer Biology The University of Melbourne St Vincents Institute of Medical Research University of South Australia

About

Timothy R. Hercus is an author at South Australia Pathology specializing in cell biology, medicine, and immunology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	837
2	Cell Biology	10	10	837
3	Natural Sciences	4	4	146
4	Allergy	2	2	56
5	Biochemistry	1	1	66

Timothy R. Hercus

Publications

1.4K

Citations

H-Index

Page 1

	Year	Citations
The Structure of the GM-CSF Receptor Complex Reveals a Distinct Mode of Cytokine Receptor Activation Guido Hansen, Timothy R. Hercus, Barbara J. McClure, Cell InflammationCytokine Receptor ActivationGm-csf Receptor ComplexCytokineSignal Transduction	2008	302
Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF. Joanna M. Woodcock, B. Zacharakis, Geert Plaetinck, The EMBO Journal InflammationCytokineSignal TransductionAutoimmune DiseaseG Protein-coupled Receptor	1994	115
Residue 21 of human granulocyte-macrophage colony-stimulating factor is critical for biological activity and for high but not low affinity binding. Angel F. López, M Shannon, Timothy R. Hercus, The EMBO Journal Biological ActivityInflammationLow Affinity BindingCytokineGranulocyte	1992	112
Specific human granulocyte-macrophage colony-stimulating factor antagonists. Timothy R. Hercus, C.J. Bagley, Bronwyn Cambareri, Proceedings of the National Academy of Sciences ImmunologyEscherichia ColiImmunologic MechanismImmune SystemMyeloid Neoplasia	1994	106
Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit Michelle Perugini, Anna Brown, Diana Salerno, Blood	2010	67
Sphingosine Activates Protein Kinase A Type II by a Novel cAMP-independent Mechanism Yuefang Ma, Stuart M. Pitson, Timothy R. Hercus, Journal of Biological Chemistry Molecular BiologyCytoskeletonPka ActivationCellular PhysiologySignaling Pathway	2005	66
Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis Denis Tvorogov, Danièl Thomas, Nicholas P. D. Liau, Science Advances	2018	58
Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer Antibody Sophie E. Broughton, Timothy R. Hercus, Matthew P. Hardy, Cell Reports	2014	57
Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling Sophie E. Broughton, Timothy R. Hercus, Tracy L. Nero, Structure Affinity ConversionSignal TransductionSignaling PathwayG Protein-coupled ReceptorNatural Sciences	2016	53
Structure of the activation domain of the GM-CSF/IL-3/IL-5 receptor common β-chain bound to an antagonist Jamie Rossjohn, William J. McKinstry, Joanna M. Woodcock, Blood	2000	52

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