B. Zacharakis

Three residues in the common beta chain of the human GM‐CSF, IL‐3 and IL‐5 receptors are essential for GM‐CSF and IL‐5 but not IL‐3 high affinity binding and interact with Glu21 of GM‐CSF.

Joanna M. Woodcock, B. Zacharakis, Geert Plaetinck et al. · The EMBO Journal · 1994 · 115 citations · Full text

Life Sciences, Immunology, Molecular Biology +7

A Single Tyrosine Residue in the Membrane-proximal Domain of the Granulocyte-Macrophage Colony-stimulating Factor, Interleukin (IL)-3, and IL-5 Receptor Common β-Chain Is Necessary and Sufficient for High Affinity Binding and Signaling by All Three Ligands

Joanna M. Woodcock, Christopher J. Bagley, B. Zacharakis et al. · Journal of Biological Chemistry · 1996 · 91 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Identification of a Cys Motif in the Common β Chain of the Interleukin 3, Granulocyte-Macrophage Colony-stimulating Factor, and Interleukin 5 Receptors Essential for Disulfide-linked Receptor Heterodimerization and Activation of All Three Receptors

Frank C. Stomski, Joanna M. Woodcock, B. Zacharakis et al. · Journal of Biological Chemistry · 1998 · 57 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Simultaneous Antagonism of Interleukin-5, Granulocyte-Macrophage Colony-Stimulating Factor, and Interleukin-3 Stimulation of Human Eosinophils by Targetting the Common Cytokine Binding Site of Their Receptors

Qing‐Yuan Sun, Karen L. Jones, Barbara J. McClure et al. · Blood · 1999 · 56 citations

Life Sciences, Immunology, Pharmacology +17

Simultaneous Antagonism of Interleukin-5, Granulocyte-Macrophage Colony-Stimulating Factor, and Interleukin-3 Stimulation of Human Eosinophils by Targetting the Common Cytokine Binding Site of Their Receptors

Qing‐Yuan Sun, Karen L. Jones, Barbara J. McClure et al. · Blood · 1999 · 53 citations

Life Sciences, Immunology, Pharmacology +17