Notch1 endocytosis is induced by ligand and is required for signal transduction

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Bart De Strooper, Wim Annaert, Philippe Cupers et al. · Nature · 1999 · 2.1K citations

Protein Secretion, Protein Function, Signal Transduction +8

Dynasore, a Cell-Permeable Inhibitor of Dynamin

Eric Macia, Marcelo Ehrlich, Ramiro Massol et al. · Developmental Cell · 2006 · 2K citations · Full text

Biochemistry, Medicine, Mechanism Of Action +8

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Eric H. Schroeter, Jeffrey A. Kisslinger, Raphael Kopan · Nature · 1998 · 1.6K citations

Signal Transduction, Signaling Pathway, Cell Interaction +6

Signalling downstream of activated mammalian Notch

Sophie Jarriault, Christel Brou, Frédérique Logeat et al. · Nature · 1995 · 1.4K citations

Developmental Biology, Signal Transduction, Signaling Pathway +8

Induction of mutant dynamin specifically blocks endocytic coated vesicle formation.

Hanna Damke, Toru Baba, Dale E. Warnock et al. · The Journal of Cell Biology · 1994 · 1.2K citations

Molecular Biology, Coated Vesicles, Cellular Physiology +18