Alexander C. James

Bacterially Derived 400 nm Particles for Encapsulation and Cancer Cell Targeting of Chemotherapeutics

Jennifer A. MacDiarmid, Nancy B. Amaro-Mugridge, Jocelyn Weiss et al. · Cancer Cell · 2007 · 290 citations · Full text

Nanoparticles, Nanomedicine, Nanotherapeutics +9

Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cells.

Brian Raught, Anne‐Claude Gingras, Alexander C. James et al. · PubMed · 1996 · 109 citations

Breast Oncology, Dominant-negative Isoform, Cancer Biology +17

Notch4 reveals a novel mechanism regulating Notch signal transduction

Alexander C. James, Justin O. Szot, Kala Iyer et al. · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2014 · 75 citations

Signal Transduction, Signaling Pathway, Molecular Pathway +5

Induction of matrix metalloproteinases MMP-1 and MMP-2 by co-culture of breast cancer cells and bone marrow fibroblasts

Sonia Saad, Linda J. Bendall, Alexander C. James et al. · Breast Cancer Research and Treatment · 2000 · 49 citations

Breast Oncology, Bone Marrow Fibroblasts, Medicine +14

PGRMC1 phosphorylation affects cell shape, motility, glycolysis, mitochondrial form and function, and tumor growth

Bashar M. Thejer, Partho P. Adhikary, Amandeep Kaur et al. · BMC Molecular and Cell Biology · 2020 · 43 citations · Full text