Receptor Internalization

Receptor Internalization is a cellular trafficking process in which cell-surface receptors are removed from the plasma membrane via endocytosis into intracellular compartments, typically following ligand binding, thereby modulating receptor signaling, resensitization, and downregulation.

2.8K

Publications

243.8K

Citations

9.9K

Authors

1.8K

Institutions

Publications per year

2017–2026

217

Parents

Molecular Pharmacology

Children

Constitutive InternalizationDynamin-dependent InternalizationEndocytic Motif RecognitionEndocytic Pathway RegulationG-protein-coupled Receptor InternalizationLigand-induced EndocytosisMembrane Receptor TraffickingTyrosine Kinase Receptor Internalizationβ-Arrestin-mediated Internalization

Publications

2.8K

Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: Selective externalization of the receptor

Bin‐Tao Pan, Rose M. Johnstone · Cell · 1983 · 2K citations

Life Sciences, Biochemistry, Cell Biology +10

The Nature of the Arrestin·Receptor Complex Determines the Ultimate Fate of the Internalized Receptor

Ling Pan, Eugenia V. Gurevich, Vsevolod V. Gurevich · Journal of Biological Chemistry · 2003 · 1.8K citations · Full text

Life Sciences, Biochemistry, Pharmacology +13

Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes.

Clifford V. Harding, John E. Heuser, Philip D. Stahl · The Journal of Cell Biology · 1983 · 1.7K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

Oscar B. Goodman, Jason G. Krupnick, Francesca Santini et al. · Nature · 1996 · 1.4K citations

Life Sciences, Cell Biology, Physiology +16

Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes.

Bin Pan, Katie Teng, Chia‐Lun Wu et al. · The Journal of Cell Biology · 1985 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

1–5 of 2.8K

Authors

9.9K

AS
Alexander Sorkin
University of Pittsburgh, United States
31 publications · 4.2K citations
29
h-index
MV
Mark von Zastrow
University of California, San Francisco, United States
32 publications · 4.9K citations
26
h-index
NW
Nigel W. Bunnett
University of California, San Francisco, United States
26 publications · 3.4K citations
24
h-index
JB
Jeffrey Benovic
Thomas Jefferson University, United States
23 publications · 3.7K citations
22
h-index
RJ
Robert J. Lefkowitz
Duke Medical Center, United States
22 publications · 4.7K citations
22
h-index

1–5 of 9.9K

Institutions

1.8K

1–8 of 1.8K

Venues

Journal of Biological Chemistry
JBC · 533 publications · 58.7K citations
129
h-index
The Journal of Cell Biology
JCB · 131 publications · 22.8K citations
84
h-index
Proceedings of the National Academy of Sciences
PNAS · 92 publications · 14.7K citations
66
h-index
Journal of Cell Science
79 publications · 6.1K citations
49
h-index
Molecular Biology of the Cell
MBC · 73 publications · 6.7K citations
48
h-index

1–5