Novel thiol-based histone deacetylase inhibitors bearing 3-phenyl-1H-pyrazole-5-carboxamide scaffold as surface recognition motif: Design, synthesis and SAR study

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

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Functional Differences in Epigenetic ModulatorsSuperiority of Mercaptoacetamide-Based Histone Deacetylase Inhibitors Relative to Hydroxamates in Cortical Neuron Neuroprotection Studies

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Highly Potent and Selective Histone Deacetylase 6 Inhibitors Designed Based on a Small-Molecular Substrate

Takayoshi Suzuki, Akiyasu Kouketsu, Yukihiro Itoh et al. · Journal of Medicinal Chemistry · 2006 · 104 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Design, Synthesis, Structure−Selectivity Relationship, and Effect on Human Cancer Cells of a Novel Series of Histone Deacetylase 6-Selective Inhibitors

Yukihiro Itoh, Takayoshi Suzuki, Akiyasu Kouketsu et al. · Journal of Medicinal Chemistry · 2007 · 102 citations · Full text

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Thiol-based SAHA analogues as potent histone deacetylase inhibitors

Takayoshi Suzuki, Akiyasu Kouketsu, Azusa Matsuura et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 92 citations · Full text

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