Miguel A. Ondetti

Design of Specific Inhibitors of Angiotensin-Converting Enzyme: New Class of Orally Active Antihypertensive Agents

Miguel A. Ondetti, Bernard Rubin, David W. Cushman · Science · 1977 · 1.9K citations

Hypertension, Cardiovascular Pharmacology, Pharmacotherapy +16

Design of potent competitive inhibitors of angiotensin-converting enzyme. Carboxyalkanoyl and mercaptoalkanoyl amino acids

David W. Cushman, H.S. Cheung, Emily F. Sabo et al. · Biochemistry · 1977 · 900 citations

Cardiovascular Pharmacology, Altmetric Attention Score, Pharmacotherapy +17

Binding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence.

H.S. Cheung, F.L. Wang, Miguel A. Ondetti et al. · Journal of Biological Chemistry · 1980 · 740 citations · Full text

Structure.nh2-terminal Glycyl Dipeptides, Same Cooh-terminal Dipeptides, Peptide Science +17

Angiotensin-converting enzyme inhibitors from the venom of Bothrops jararaca. Isolation, elucidation of structure, and synthesis

Miguel A. Ondetti, Nina J. Williams, Emily F. Sabo et al. · Biochemistry · 1971 · 520 citations

Molecular Pharmacology, Medicinal Chemistry, Biosynthesis +15

History of the design of captopril and related inhibitors of angiotensin converting enzyme.

David W. Cushman, Miguel A. Ondetti · Hypertension · 1991 · 262 citations

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +12